Have you done a general clean up...empty temp files and the like?
How about a defrag?
One thing I note running on the computer is Skype. While the program itself is fine it IS a major resource hog and will definitely slow the computer.
I would recommend turning this off except when you are using it and also disable the auto start when Windows boots up, this definitely slows start time. Discovered this on my daughter's computer when she complained of sudden slow downs and freezing on boot.
Turned off the Skype program and that all stopped.
Open the Skype program and there is a box with a check mark in it which says Start when Windows starts. Take that check mark out of there and reboot the computer.
Skype can very easily be run manually when you want to do it.
Also what is this CurseClient program?
You are also running the very old version of HJT. Remove that one and download the newest version from HERE
Save it to the desktop and then doubleclick to run the program. Do a full system scan with it and save the log and post it here.