Download this file, Pocket Killbox

Extract it, and run the killbox.exe file. When it loads copy the full path to the file you would like to delete in the field and press the Delete File button (looks like a red circle with a white X). It will prompt you to reboot, allow it to do so, and hopefully your file will now be deleted.

These are the files you need to insert into the delete field, you should be able to copy/paste them in by highlighting them, then choose copy and then paste them into the field;

C:\!KillBox\weather.exe
C:\Documents and Settings\All Users\Application Data\Microsoft\Network\Downloader\qmgr0.dat
C:\Documents and Settings\All Users\Application Data\Microsoft\Network\Downloader\qmgr1.dat
C:\Documents and Settings\All Users\Application Data\Spybot - Search & Destroy\Recovery\WinFixer.zip/UWFX5_0001_LP1014NetInstaller.exe
C:\Documents and Settings\All Users\Application Data\Spybot - Search & Destroy\Recovery\WinFixer.zip
C:\Documents and Settings\Debs\Desktop\My Downloads\delightfuldolphins.exe/WISE0019.BIN
C:\Documents and Settings\Debs\Desktop\My Downloads\delightfuldolphins.exe/WISE0020.BIN
C:\Documents and Settings\Debs\Desktop\My Downloads\delightfuldolphins.exe/WISE0021.BIN
C:\Documents and Settings\Debs\Desktop\My Downloads\delightfuldolphins.exe/WISE0022.BIN
C:\Documents and Settings\Debs\Desktop\My Downloads\delightfuldolphins.exe WiseSFX
C:\Documents and Settings\Debs\My Documents\My Received Files\vnc-4.0-x86_win32.exe/data0002
C:\Documents and Settings\Debs\My Documents\My Received Files\vnc-4.0-x86_win32.exe/data0003
C:\Documents and Settings\Debs\My Documents\My Received Files\vnc-4.0-x86_win32.exe/data0006
C:\Documents and Settings\Debs\My Documents\My Received Files\vnc-4.0-x86_win32.exe Inno
C:\Documents and Settings\Keith\Local Settings\Temp\!update.exe
C:\Documents and Settings\Keith\Local Settings\Temp\Free Download Manager\tic6D3E.tmp
C:\Documents and Settings\Keith\Local Settings\Temp\~DF881A.tmp
C:\Documents and Settings\Keith\Local Settings\Temp\~DFBBC4.tmp
C:\Documents and Settings\Keith\Local Settings\Temporary Internet Files\Content.IE5\STUNSLE3\!update-4295[1].0000
C:\Program Files\mIRC\mirc.exe
C:\Program Files\Μicrosoft\winlogon.exe
C:\WINDOWS\system32\klktrpej.dll
C:\WINDOWS\system32\tlwwncoq.exe

Once you have completed the above and rebooted then run a new Kaspersky scan, save the log and then run a new HJT scan and post both logs here.